Mengting Ai

Patient-clinician communication is an asymmetric-information problem: patients often do not disclose fears, misconceptions, or practical barriers unless clinicians elicit them skillfully. Effective medical dialogue therefore requires reasoning under partial observability: clinicians must elicit latent concerns, confirm them through interaction, and respond in ways that guide patients toward appropriate care. However, existing medical dialogue benchmarks largely sidestep this challenge by exposing hidden patient state, collapsing elicitation into extraction, or evaluating responses without modeling what remains hidden. We present MedConceal, a benchmark with an interactive patient simulator for evaluating hidden-concern reasoning in medical dialogue, comprising 300 curated cases and 600 clinician-LLM interactions. Built from clinician-answered online health discussions, each case pairing clinician-visible context with simulator-internal hidden concerns derived from prior literature and structured using an expert-developed taxonomy. The simulator withholds these concerns from the dialogue agent, tracks whether they have been revealed and addressed via theory-grounded turn-level communication signals, and is clinician-reviewed for clinical plausibility. This enables process-aware evaluation of both task success and the interaction process that leads to it. We study two abilities: confirmation, surfacing hidden concerns through multi-turn dialogue, and intervention, addressing the primary concern and guiding the patient toward a target plan. Results show that no single system dominates: frontier models lead on different confirmation metrics, while human clinicians (N=159) remain strongest on intervention success. Together, these results identify hidden-concern reasoning under partial observability as a key unresolved challenge for medical dialogue systems.

While structured pruning presents a highly effective pathway for accelerating Large Language Model (LLM) inference, existing methods frequently suffer from significant performance degradation and demand computationally retraining to recover capabilities. To overcome these barriers, we present NIRVANA, a novel, hardware-aware structured pruning framework designed to preserve both zero-shot performance and the optimization landscape for downstream fine-tuning. Departing from traditional loss-based heuristics, our approach evaluates structural importance through a first-order function-space saliency inspired by the Neural Tangent Kernel (NTK), effectively safeguarding the model's critical training dynamics. To prevent structural collapse at high compression rates, we introduce a global unit-ranking strategy coupled with an analytically derived allocation mechanism, which optimally balances the pruning aggressiveness between attention heads and MLP neurons. Furthermore, we eliminate the instability typically associated with random data sampling by employing a lightweight, KL-divergence-driven calibration data selection process. Extensive evaluations across Llama3, Qwen, and T5 architectures demonstrate that NIRVANA consistently establishes new state-of-the-art results on different benchmarks, providing a theoretically sound and practical approach to LLM compression.