作者位次 #5/8ACL 2026Findings· Findings of ACL
L ipo A gent: Coordinating Fine-Tuned LLM Agents for Safer Lipid Design
Leshu Li · An Lu · Haiyu Wang · Zhibin Feng · Conghui Duan · Qing Bao · Zongmin Zhao · Sai Qian Zhang
摘要
Lipid nanoparticles (LNPs) are among the most clinically mature platforms for nucleic acid delivery, yet designing lipids that are both effective and biologically safe remains a major bottleneck. In practical screening, toxicity is a decision-level constraint: if a lipid is toxic, its efficiency...