Tong Ruan

Instruction tuning plays a crucial role in enhancing large language models (LLMs) to better understand complex user instructions. While various data selection and revision methods have been explored to optimize instruction tuning datasets, they face two main challenges: unreasonable pruning of po...

Artificial intelligence doctor assistants (AIDAs) help streamline clinical decision-making and reduce physician workload. While existing systems primarily utilize Large Language Models (LLMs) or retrieval-augmented generation (RAG), these methods typically retrieve static facts—whether as text pa...

Large language models (LLMs) offer a new paradigm for molecular property prediction (MPP), yet a semantic gap between natural language and molecular representations limits LLMs’ ability to capture structure–activity relationships (SAR). Recent approaches have explored injecting structure-level in...

Training large language models for domain adaptation poses a significant challenge in balancing the acquisition of domain knowledge with the retention of general abilities, often leading to catastrophic forgetting. While curriculum learning offers a promising direction, conventional methods typic...

Large language models (LLMs) have been widely adopted in healthcare, yet they still encounter significant challenges in complex clinical decision-making scenarios. Existing benchmarks primarily assess LLM performance in single-course settings and lack systematic evaluation in multi-course scenari...

With the remarkable performance of large language models (LLMs) in medicine, particularly their ability to support clinical decision-making in medical dialogues, a key limitation remains: the static reasoning patterns derived from human expert experience are often inadequate for the dynamic and d...

Medical visual question answering (MedVQA) requires models to provide accurate answers given a medical image and a corresponding question. Recently, instruction tuning of general large vision–language models (LVLMs) has become a dominant paradigm for this task, enabling open-ended predictions and...

Biomedical data-to-text generation aims at generating textual natural language descriptions that can fluently and precisely describe the biomedical structured data. However, biomedical data-to-text generation faces the dilemma of a lack of labeled data due to the privacy and scarcity of medical d...